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Rammohan said that studies are planned that will examine the use of modafinil in chronic fatigue syndrome and fatigue associated with chemotherapy.

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In addition to its wakefulness-promoting effects and increased locomotor activity in animals, in humans, PROVIGIL produces psychoactive and euphoric effects, alterations in mood, perception, thinking, and feelings typical of other CNS stimulants.

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Eugeroics have been designed to treat narcolepsy (sleeping in the day), hypersomnia (excessive sleep) and catoplexy (a condition of sudden muscular weakness or fatigue).

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Assessments were the Epworth Sleepiness Scale, Brief Fatigue Inventory, Clinical Global Impression of Improvement scale, 17-item Hamilton Rating Scale for Depression, and Montgomery-Asberg Depression Rating Scale.

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